Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Krt14  keratin 14   (Synonyms: Cytokeratin 14, epidermolysis bullosa simplex, Dowling-Meara, Koebner, K14, Krt-1.14, Krt1-14)
Results	Reference
1*	J:176660 Abler LL, Keil KP, Mehta V, Joshi PS, Schmitz CT, Vezina CM, A high-resolution molecular atlas of the fetal mouse lower urogenital tract. Dev Dyn. 2011 Oct;240(10):2364-77
1*	J:255611 Adhikari N, Neupane S, Roh J, Jun JH, Jung JK, Sohn WJ, Kim JY, Kim JY, Immunolocalization patterns of cytokeratins during salivary acinar cell development in mice. J Mol Histol. 2018 Feb;49(1):1-15
1*	J:99569 Barrow KM, Ward CM, Rutter J, Ali S, Stern PL, Embryonic expression of murine 5T4 oncofoetal antigen is associated with morphogenetic events at implantation and in developing epithelia. Dev Dyn. 2005 Aug;233(4):1535-45
1	J:262819 Bohnenpoll T, Feraric S, Nattkemper M, Weiss AC, Rudat C, Meuser M, Trowe MO, Kispert A, Diversification of Cell Lineages in Ureter Development. J Am Soc Nephrol. 2017 Jun;28(6):1792-1801
1	J:318638 Chen B, Wang HL, Chen R, Chen L, Yang S, Wang Y, Xue ZF, An L314Q mutation in Map3k1 gene results in failure of eyelid fusion in the N-ethyl-N-nitrosourea-induced mutant line. Exp Anim. 2021;70(4):459-468
1	J:218613 Chen J, Laclef C, Moncayo A, Snedecor ER, Yang N, Li L, Takemaru K, Paus R, Schneider-Maunoury S, Clark RA, The ciliopathy gene rpgrip1l is essential for hair follicle development. J Invest Dermatol. 2015 Mar;135(3):701-9
1*	J:142873 Collins CA, Watt FM, Dynamic regulation of retinoic acid-binding proteins in developing, adult and neoplastic skin reveals roles for beta-catenin and Notch signalling. Dev Biol. 2008 Dec 1;324(1):55-67
1	J:95347 Daniely Y, Liao G, Dixon D, Linnoila RI, Lori A, Randell SH, Oren M, Jetten AM, Critical role of p63 in the development of a normal esophageal and tracheobronchial epithelium. Am J Physiol Cell Physiol. 2004 Jul;287(1):C171-81
1	J:143960 Descargues P, Sil AK, Sano Y, Korchynskyi O, Han G, Owens P, Wang XJ, Karin M, IKKalpha is a critical coregulator of a Smad4-independent TGFbeta-Smad2/3 signaling pathway that controls keratinocyte differentiation. Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2487-92
1	J:183190 Fehrenschild D, Galli U, Breiden B, Bloch W, Schettina P, Brodesser S, Michels C, Gunschmann C, Sandhoff K, Niessen CM, Niemann C, TCF/Lef1-mediated control of lipid metabolism regulates skin barrier function. J Invest Dermatol. 2012 Feb;132(2):337-45
1	J:334122 Glover JD, Sudderick ZR, Shih BB, Batho-Samblas C, Charlton L, Krause AL, Anderson C, Riddell J, Balic A, Li J, Klika V, Woolley TE, Gaffney EA, Corsinotti A, Anderson RA, Johnston LJ, Brown SJ, Wang S, Chen Y, Crichton ML, Headon DJ, The developmental basis of fingerprint pattern formation and variation. Cell. 2023 Mar 2;186(5):940-956.e20
1	J:258233 Guo D, Yuan Z, Ru J, Gu X, Zhang W, Mao F, Ouyang H, Wu K, Liu Y, Liu C, A Spatiotemporal Requirement for Prickle 1-Mediated PCP Signaling in Eyelid Morphogenesis and Homeostasis. Invest Ophthalmol Vis Sci. 2018 Feb 1;59(2):952-966
1	J:112798 Han G, Li AG, Liang YY, Owens P, He W, Lu S, Yoshimatsu Y, Wang D, Ten Dijke P, Lin X, Wang XJ, Smad7-induced beta-catenin degradation alters epidermal appendage development. Dev Cell. 2006 Sep;11(3):301-12
1	J:315539 Hu L, Liu J, Li Z, Ozturk F, Gurumurthy C, Romano RA, Sinha S, Nawshad A, TGFbeta3 regulates periderm removal through DeltaNp63 in the developing palate. J Cell Physiol. 2015 Jun;230(6):1212-25
1	J:272927 Inaba H, Yamakawa D, Tomono Y, Enomoto A, Mii S, Kasahara K, Goto H, Inagaki M, Regulation of keratin 5/14 intermediate filaments by CDK1, Aurora-B, and Rho-kinase. Biochem Biophys Res Commun. 2018 Apr 6;498(3):544-550
1	J:83259 Jaubert J, Cheng J, Segre JA, Ectopic expression of kruppel like factor 4 (Klf4) accelerates formation of the epidermal permeability barrier. Development. 2003 Jun;130(12):2767-77
1	J:282774 Jia X, Min L, Zhu S, Zhang S, Huang X, Loss of sonic hedgehog gene leads to muscle development disorder and megaesophagus in mice. FASEB J. 2018 Oct;32(10):5703-5715
1	J:304850 Jiang C, Javed A, Kaiser L, Nava MM, Xu R, Brandt DT, Zhao D, Mayer B, Fernandez-Baldovinos J, Zhou L, Hoss C, Sawmynaden K, Oleksy A, Matthews D, Weinstein LS, Hahn H, Grone HJ, Graumann PL, Niessen CM, Offermanns S, Wickstrom SA, Worzfeld T, Mechanochemical control of epidermal stem cell divisions by B-plexins. Nat Commun. 2021 Feb 26;12(1):1308
1	J:125902 Koster MI, Dai D, Marinari B, Sano Y, Costanzo A, Karin M, Roop DR, p63 induces key target genes required for epidermal morphogenesis. Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3255-60
1	J:244349 Kousa YA, Moussa D, Schutte BC, IRF6 expression in basal epithelium partially rescues Irf6 knockout mice. Dev Dyn. 2017 Sep;246(9):670-681
1	J:225061 Kouskoura T, Kozlova A, Alexiou M, Blumer S, Zouvelou V, Katsaros C, Chiquet M, Mitsiadis TA, Graf D, The etiology of cleft palate formation in BMP7-deficient mice. PLoS One. 2013;8(3):e59463
1	J:257613 Kuony A, Michon F, Epithelial Markers aSMA, Krt14, and Krt19 Unveil Elements of Murine Lacrimal Gland Morphogenesis and Maturation. Front Physiol. 2017;8:739
1	J:290414 Li J, Gordon J, Chen ELY, Xiao S, Wu L, Zuniga-Pflucker JC, Manley NR, NOTCH1 signaling establishes the medullary thymic epithelial cell progenitor pool during mouse fetal development. Development. 2020 Jun 22;147(12):dev178988
1	J:231070 Liu Y, Snedecor ER, Choi YJ, Yang N, Zhang X, Xu Y, Han Y, Jones EC, Shroyer KR, Clark RA, Zhang L, Qin C, Chen J, Gorab Is Required for Dermal Condensate Cells to Respond to Hedgehog Signals during Hair Follicle Morphogenesis. J Invest Dermatol. 2016 Feb;136(2):378-86
1	J:219800 Lungova V, Verheyden JM, Herriges J, Sun X, Thibeault SL, Ontogeny of the mouse vocal fold epithelium. Dev Biol. 2015 Mar 15;399(2):263-82
1*	J:316269 Mehta V, Schmitz CT, Keil KP, Joshi PS, Abler LL, Lin TM, Taketo MM, Sun X, Vezina CM, Beta-catenin (CTNNB1) induces Bmp expression in urogenital sinus epithelium and participates in prostatic bud initiation and patterning. Dev Biol. 2013 Apr 15;376(2):125-35
1	J:175603 Mejetta S, Morey L, Pascual G, Kuebler B, Mysliwiec MR, Lee Y, Shiekhattar R, Di Croce L, Benitah SA, Jarid2 regulates mouse epidermal stem cell activation and differentiation. EMBO J. 2011;30(17):3635-46
1	J:216505 Meng Q, Mongan M, Wang J, Tang X, Zhang J, Kao W, Xia Y, Epithelial sheet movement requires the cooperation of c-Jun and MAP3K1. Dev Biol. 2014 Nov 1;395(1):29-37
1	J:100687 Mill P, Mo R, Hu MC, Dagnino L, Rosenblum ND, Hui CC, Shh controls epithelial proliferation via independent pathways that converge on N-Myc. Dev Cell. 2005 Aug;9(2):293-303
1	J:74117 Montenegro MA, Rojas M, Dominguez S, Vergara A, Cytokeratin, vimentin and E-cadherin immunodetection in the embryonic palate in two strains of mice with different susceptibility to glucocorticoid-induced clefting. J Craniofac Genet Dev Biol. 2000 Jul-Sep;20(3):137-43
1	J:210855 Moriyama M, Moriyama H, Uda J, Matsuyama A, Osawa M, Hayakawa T, BNIP3 plays crucial roles in the differentiation and maintenance of epidermal keratinocytes. J Invest Dermatol. 2014 Jun;134(6):1627-35
1	J:124280 Nieuwenhuis E, Barnfield PC, Makino S, Hui CC, Epidermal hyperplasia and expansion of the interfollicular stem cell compartment in mutant mice with a C-terminal truncation of Patched1. Dev Biol. 2007 Aug 15;308(2):547-60
1	J:112169 Nieuwenhuis E, Motoyama J, Barnfield PC, Yoshikawa Y, Zhang X, Mo R, Crackower MA, Hui CC, Mice with a targeted mutation of patched2 are viable but develop alopecia and epidermal hyperplasia. Mol Cell Biol. 2006 Sep;26(17):6609-22
1	J:240059 Park KC, Lee M, Jeon Y, Jeon R, Baek SH, Lee H, Kim KI, Skin-Specific Deletion of Mis18alpha Impedes Proliferation and Stratification of Epidermal Keratinocytes. J Invest Dermatol. 2017 Feb;137(2):414-421
1	J:301537 Park KC, Park JH, Baek SH, Kim KI, Pontin-deficiency causes senescence in fibroblast cells and epidermal keratinocytes but induces apoptosis in cancer cells. Biochim Biophys Acta Mol Cell Res. 2020 Sep;1867(9):118740
1	J:342315 Rao J, Djeffal Y, Chal J, Marchiano F, Wang CH, Al Tanoury Z, Gapon S, Mayeuf-Louchart A, Glass I, Sefton EM, Habermann B, Kardon G, Watt FM, Tseng YH, Pourquie O, Reconstructing human brown fat developmental trajectory in vitro. Dev Cell. 2023 Nov 6;58(21):2359-2375.e8
1	J:166768 Rodriguez P, Da Silva S, Oxburgh L, Wang F, Hogan BL, Que J, BMP signaling in the development of the mouse esophagus and forestomach. Development. 2010 Dec;137(24):4171-6
1	J:181275 Romano RA, Smalley K, Magraw C, Serna VA, Kurita T, Raghavan S, Sinha S, DeltaNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation. Development. 2012 Feb;139(4):772-82
1	J:163649 Sani FV, Kaartinen V, El Shahawy M, Linde A, Gritli-Linde A, Developmental changes in cellular and extracellular structural macromolecules in the secondary palate and in the nasal cavity of the mouse. Eur J Oral Sci. 2010 Jun;118(3):221-36
1	J:301269 Sankoda N, Tanabe W, Tanaka A, Shibata H, Woltjen K, Chiba T, Haga H, Sakai Y, Mandai M, Yamamoto T, Yamada Y, Uemoto S, Kawaguchi Y, Epithelial expression of Gata4 and Sox2 regulates specification of the squamous-columnar junction via MAPK/ERK signaling in mice. Nat Commun. 2021 Jan 25;12(1):560
1	J:277246 Sarper SE, Inubushi T, Kurosaka H, Ono Minagi H, Murata Y, Kuremoto KI, Sakai T, Taniuchi I, Yamashiro T, Anterior cleft palate due to Cbfb deficiency and its rescue by folic acid. Dis Model Mech. 2019 Jun 27;12(6):dmm038851
1	J:341642 Schwartz B, Levi H, Menon G, Maria R, Upcher A, Kotlovski Y, Oss-Ronen L, Cohen I, ZNF750 Regulates Skin Barrier Function by Driving Cornified Envelope and Lipid Processing Pathways. J Invest Dermatol. 2023 Sep 3;
1	J:254700 Seo S, Chen L, Liu W, Zhao D, Schultz KM, Sasman A, Liu T, Zhang HF, Gage PJ, Kume T, Foxc1 and Foxc2 in the Neural Crest Are Required for Ocular Anterior Segment Development. Invest Ophthalmol Vis Sci. 2017 Mar 1;58(3):1368-1377
1	J:181974 Seo S, Singh HP, Lacal PM, Sasman A, Fatima A, Liu T, Schultz KM, Losordo DW, Lehmann OJ, Kume T, Forkhead box transcription factor FoxC1 preserves corneal transparency by regulating vascular growth. Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):2015-20
1	J:346597 Seo S, Sonn SK, Kweon HY, Jin J, Kume T, Ko JY, Park JH, Oh GT, Primary Cilium in Neural Crest Cells Crucial for Anterior Segment Development and Corneal Avascularity. Invest Ophthalmol Vis Sci. 2024 Mar 5;65(3):30
1	J:237499 Sima J, Piao Y, Chen Y, Schlessinger D, Molecular dynamics of Dkk4 modulates Wnt action and regulates meibomian gland development. Development. 2016 Dec 15;143(24):4723-4735
1	J:264370 Sima J, Yan Z, Chen Y, Lehrmann E, Zhang Y, Nagaraja R, Wang W, Wang Z, Schlessinger D, Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178
1*	J:159506 Sun P, Yuan Y, Li A, Li B, Dai X, Cytokeratin expression during mouse embryonic and early postnatal mammary gland development. Histochem Cell Biol. 2010 Feb;133(2):213-21
1	J:238904 Suzuki D, Sahu R, Leu NA, Senoo M, The carboxy-terminus of p63 links cell cycle control and the proliferative potential of epidermal progenitor cells. Development. 2015 Jan 15;142(2):282-90
1	J:256856 Szymaniak AD, Mi R, McCarthy SE, Gower AC, Reynolds TL, Mingueneau M, Kukuruzinska M, Varelas X, The Hippo pathway effector YAP is an essential regulator of ductal progenitor patterning in the mouse submandibular gland. Elife. 2017 May 11;6:e23499
1*	J:108338 Tanifuji-Terai N, Terai K, Hayashi Y, Chikama T, Kao WW, Expression of keratin 12 and maturation of corneal epithelium during development and postnatal growth. Invest Ophthalmol Vis Sci. 2006 Feb;47(2):545-51
1*	J:117802 Troy TC, Li Y, O'malley L, Turksen K, The temporal and spatial expression of Claudins in epidermal development and the accelerated program of epidermal differentiation in K14-CaSR transgenic mice. Gene Expr Patterns. 2007 Feb;7(4):423-30
1	J:260842 Urwyler-Rosselet C, Tanghe G, Leurs K, Gilbert B, De Rycke R, De Bruyne M, Lippens S, Bartunkova S, De Groote P, Niessen C, Haftek M, Vandenabeele P, Declercq W, Keratinocyte-Specific Ablation of RIPK4 Allows Epidermal Cornification but Impairs Skin Barrier Formation. J Invest Dermatol. 2018 Jun;138(6):1268-1278
1	J:215769 Wang DH, Tiwari A, Kim ME, Clemons NJ, Regmi NL, Hodges WA, Berman DM, Montgomery EA, Watkins DN, Zhang X, Zhang Q, Jie C, Spechler SJ, Souza RF, Hedgehog signaling regulates FOXA2 in esophageal embryogenesis and Barrett's metaplasia. J Clin Invest. 2014 Sep 2;124(9):3767-80
1	J:169856 Xin Y, Lu Q, Li Q, IKK1 Control of Epidermal Differentiation Is Modulated by Notch Signaling. Am J Pathol. 2011 Apr;178(4):1568-77
1*	J:224085 Yang N, Li L, Eguether T, Sundberg JP, Pazour GJ, Chen J, Intraflagellar transport 27 is essential for hedgehog signaling but dispensable for ciliogenesis during hair follicle morphogenesis. Development. 2015 Jun 15;142(12):2194-202
1	J:100612 Yu WY, Slack JM, Tosh D, Conversion of columnar to stratified squamous epithelium in the developing mouse oesophagus. Dev Biol. 2005 Aug 1;284(1):157-70
1	J:125580 Zhang L, Deng M, Kao CW, Kao WW, Xia Y, MEK kinase 1 regulates c-Jun phosphorylation in the control of corneal morphogenesis. Mol Vis. 2003 Nov 3;9:584-93
1*	J:293298 Zhang M, Wang X, Guo F, Jia Q, Liu N, Chen Y, Yan Y, Huang M, Tang H, Deng Y, Huang S, Zhou Z, Zhang L, Zhang L, Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development. Theranostics. 2019;9(17):5065-5084